gRPC uses HTTP/2 as its transport protocol, which inherently supports message ordering. It maintains a single TCP connection for all requests and responses between client and server, ensuring that messages are sent and received in the order they were dispatched. This is achieved through HTTP/2’s multiplexing feature where multiple streams of data can be sent over a single TCP connection without blocking each other. Each stream has an identifier used to associate it with its request or response, preserving the sequence.