No, there are many other options.
For example — if you are a non-profit organization, a club, a church, or another non-commercial entity, you may want to register as a .org domain name.
There has been a trend among tech-focused startups and open source projects in the last few years to use the .io extension.
For non-US entities, each country has its own country-code TLD, such a .uk and .ru. These are also popular for domain hacks — using the domain extension as part of the name of your site or brand.
There also, of course, the new “exotic” domain names, such as .ninja and .club. There are a number of these, and they might fit your brand very well.
You generally want to steer clear of second-tier gTLDs such a .biz and .info. These are not very well respected and tend to make savvy internet users suspicious.
